RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-378a
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
northern blot analysis; immunohistochemistry etc.
Target
NA
Pathway
MAPK SIGNALING PATHWAY
PubMed ID
Title
MicroRNA-378 suppresses myocardial fibrosis through a paracrine mechanism at the early stage of cardiac hypertrophy following mechanical stress
Year
2018
Function
The miR-378-induced anti-fibrotic effects manifested partially through the suppression of p38 MAP kinase phosphorylation by targeting MKK6 in cardiac fibroblasts.